“Charmed” and “Who’s the Boss?” star Alyssa Milano has joined celebrities such as P. Diddy and Jessica Simpson as the latest star to promote the Proactiv skin care system.

“‘Proactiv has given me peace of mind,” said Ms. Milano about the Guthy-Renker line.

Drs. Rodan and Fields developed what was to become the first comprehensive acne skin care system of its kind: Proactiv Solution. The system combines finely milled prescription-grade acne medicine with soothing, spa-quality botanicals to create a powerful acne-fighting system, according to the company.

Ms. Milano will appear in advertisements, informercials and online.